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BDBM50273623 CHEMBL455981::N-(1H-Indol-2-ylmethyl)-N-(4-phenylbutyl)amine

SMILES: C(CCc1ccccc1)CNCc1cc2ccccc2[nH]1

InChI Key: InChIKey=OLWLANFDDNVPCZ-UHFFFAOYSA-N

Data: 3 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273623   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoamine oxidase


(Bos taurus)
BDBM50273623
PNG
(CHEMBL455981 | N-(1H-Indol-2-ylmethyl)-N-(4-phenyl...)
Show SMILES C(CCc1ccccc1)CNCc1cc2ccccc2[nH]1
Show InChI InChI=1S/C19H22N2/c1-2-8-16(9-3-1)10-6-7-13-20-15-18-14-17-11-4-5-12-19(17)21-18/h1-5,8-9,11-12,14,20-21H,6-7,10,13,15H2
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MMDB

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PC cid
PC sid
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Similars

Article
PubMed
1.00E+4n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of bovine brain mitochondrial MAO-A by fluorometric assay


Bioorg Med Chem 16: 9729-40 (2008)


Article DOI: 10.1016/j.bmc.2008.09.072
BindingDB Entry DOI: 10.7270/Q20001ZK
More data for this
Ligand-Target Pair
Monoamine oxidase


(Bos taurus)
BDBM50273623
PNG
(CHEMBL455981 | N-(1H-Indol-2-ylmethyl)-N-(4-phenyl...)
Show SMILES C(CCc1ccccc1)CNCc1cc2ccccc2[nH]1
Show InChI InChI=1S/C19H22N2/c1-2-8-16(9-3-1)10-6-7-13-20-15-18-14-17-11-4-5-12-19(17)21-18/h1-5,8-9,11-12,14,20-21H,6-7,10,13,15H2
PDB
MMDB

Reactome pathway
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UniProtKB/SwissProt

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GoogleScholar
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PC cid
PC sid
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Article
PubMed
>1.00E+5n/an/an/an/an/an/an/an/a



Sapienza University of Rome

Curated by ChEMBL


Assay Description
Inhibition of bovine brain mitochondrial MAO-B by fluorometric assay


Bioorg Med Chem 16: 9729-40 (2008)


Article DOI: 10.1016/j.bmc.2008.09.072
BindingDB Entry DOI: 10.7270/Q20001ZK
More data for this
Ligand-Target Pair
Amine oxidase [flavin-containing] A


(Homo sapiens (Human))
BDBM50273623
PNG
(CHEMBL455981 | N-(1H-Indol-2-ylmethyl)-N-(4-phenyl...)
Show SMILES C(CCc1ccccc1)CNCc1cc2ccccc2[nH]1
Show InChI InChI=1S/C19H22N2/c1-2-8-16(9-3-1)10-6-7-13-20-15-18-14-17-11-4-5-12-19(17)21-18/h1-5,8-9,11-12,14,20-21H,6-7,10,13,15H2
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.00E+10n/an/an/an/an/an/an/an/a



Bharati Vidyapeeth Deemed University

Curated by ChEMBL


Assay Description
Inhibition of MAO-A receptor


Bioorg Med Chem Lett 21: 2419-24 (2011)


Article DOI: 10.1016/j.bmcl.2011.02.072
BindingDB Entry DOI: 10.7270/Q2QZ2C6S
More data for this
Ligand-Target Pair