BDBM50273710 2-(4-(Biphenyl-4-ylmethylamino)-6-chloropyrimidin-2-ylthio)octanoic acid::CHEMBL462523

SMILES: CCCCCCC(Sc1nc(Cl)cc(NCc2ccc(cc2)-c2ccccc2)n1)C(O)=O

InChI Key: InChIKey=FQMPYBCEABTPIK-UHFFFAOYSA-N

Data: 7 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50273710   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase (Human)	BDBM50273710 (2-(4-(Biphenyl-4-ylmethylamino)-6-chloropyrimidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin E synthase (Human)	BDBM50273710 (2-(4-(Biphenyl-4-ylmethylamino)-6-chloropyrimidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50273710 (2-(4-(Biphenyl-4-ylmethylamino)-6-chloropyrimidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid 5-lipoxygenase (Human)	BDBM50273710 (2-(4-(Biphenyl-4-ylmethylamino)-6-chloropyrimidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin E synthase (Human)	BDBM50273710 (2-(4-(Biphenyl-4-ylmethylamino)-6-chloropyrimidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Sheep)	BDBM50273710 (2-(4-(Biphenyl-4-ylmethylamino)-6-chloropyrimidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM50273710 (2-(4-(Biphenyl-4-ylmethylamino)-6-chloropyrimidin-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>10	n/a	n/a	n/a	n/a	n/a	n/a
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