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BDBM50273820 CHEMBL515841::N-(Naphthalen-1-yl)-2-(pyridin-2-yl)quinoline-4-carboxamide

SMILES: O=C(Nc1cccc2ccccc12)c1cc(nc2ccccc12)-c1ccccn1

InChI Key: InChIKey=JHRWVWRGDXJRFM-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273820   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cytochrome P450 2C9


(Homo sapiens (Human))
BDBM50273820
PNG
(CHEMBL515841 | N-(Naphthalen-1-yl)-2-(pyridin-2-yl...)
Show SMILES O=C(Nc1cccc2ccccc12)c1cc(nc2ccccc12)-c1ccccn1
Show InChI InChI=1S/C25H17N3O/c29-25(28-21-14-7-9-17-8-1-2-10-18(17)21)20-16-24(23-13-5-6-15-26-23)27-22-12-4-3-11-19(20)22/h1-16H,(H,28,29)
PDB
MMDB

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Similars

Article
PubMed
1.32E+3n/an/an/an/an/an/an/an/a



Washington State University

Curated by ChEMBL


Assay Description
Inhibition of reconstituted CYP2C9 (unknown origin)


J Med Chem 51: 8000-11 (2008)


Article DOI: 10.1021/jm8011257
BindingDB Entry DOI: 10.7270/Q2K937CZ
More data for this
Ligand-Target Pair