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BDBM50273894 3-((3R,4S)-3-((1H-Indol-4-yl)(methyl)amino)-4-methylpiperidin-1-yl)-3-oxopropane-nitrile::CHEMBL457871

SMILES: C[C@H]1CCN(C[C@@H]1N(C)c1ncnc2[nH]ccc12)C(=O)CC#N

InChI Key: InChIKey=UJLAWZDWDVHWOW-UHFFFAOYSA-N

Data: 4 Kd

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50273894
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein kinase JAK3 (Human)	BDBM50273894 (3-((3R,4S)-3-((1H-Indol-4-yl)(methyl)amino)-4-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK2 (Human)	BDBM50273894 (3-((3R,4S)-3-((1H-Indol-4-yl)(methyl)amino)-4-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 4 (Human)	BDBM50273894 (3-((3R,4S)-3-((1H-Indol-4-yl)(methyl)amino)-4-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase 3 (Human)	BDBM50273894 (3-((3R,4S)-3-((1H-Indol-4-yl)(methyl)amino)-4-meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair