BindingDB logo
myBDB logout

BDBM50275199 CHEMBL458354::N-[4-[4-(3-Fluoro-5-methoxyphenyl)piperazin-1-yl]butyl]-2,1,3-benzoxadiazole-5-carboxamide

SMILES: COc1cc(F)cc(c1)N1CCN(CCCCNC(=O)c2ccc3nonc3c2)CC1

InChI Key: InChIKey=KIZBUXGNTYZANG-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50275199   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
D2-like dopamine receptor


(Homo sapiens (Human))
BDBM50275199
PNG
(CHEMBL458354 | N-[4-[4-(3-Fluoro-5-methoxyphenyl)p...)
Show SMILES COc1cc(F)cc(c1)N1CCN(CCCCNC(=O)c2ccc3nonc3c2)CC1
Show InChI InChI=1S/C22H26FN5O3/c1-30-19-14-17(23)13-18(15-19)28-10-8-27(9-11-28)7-3-2-6-24-22(29)16-4-5-20-21(12-16)26-31-25-20/h4-5,12-15H,2-3,6-11H2,1H3,(H,24,29)
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
658n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]spiroperidol from human cloned dopamine D3 receptor by liquid scintillation counting


Bioorg Med Chem 17: 758-66 (2009)


Article DOI: 10.1016/j.bmc.2008.11.044
BindingDB Entry DOI: 10.7270/Q2WH2PV3
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50275199
PNG
(CHEMBL458354 | N-[4-[4-(3-Fluoro-5-methoxyphenyl)p...)
Show SMILES COc1cc(F)cc(c1)N1CCN(CCCCNC(=O)c2ccc3nonc3c2)CC1
Show InChI InChI=1S/C22H26FN5O3/c1-30-19-14-17(23)13-18(15-19)28-10-8-27(9-11-28)7-3-2-6-24-22(29)16-4-5-20-21(12-16)26-31-25-20/h4-5,12-15H,2-3,6-11H2,1H3,(H,24,29)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
1.34E+3n/an/an/an/an/an/an/an/a



Università degli Studi di Bari

Curated by ChEMBL


Assay Description
Displacement of [3H]spiroperidol from human cloned dopamine D2L receptor by liquid scintillation counting


Bioorg Med Chem 17: 758-66 (2009)


Article DOI: 10.1016/j.bmc.2008.11.044
BindingDB Entry DOI: 10.7270/Q2WH2PV3
More data for this
Ligand-Target Pair