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BDBM50275583 7-ethoxy-2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine::CHEMBL520564

SMILES: CCOc1cccc2c(c(nn12)-c1ccc(F)cc1)-c1ccncc1

InChI Key: InChIKey=JMOUGAPUFGPCPC-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275583   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mitogen-activated protein kinase 14


(Homo sapiens (Human))
BDBM50275583
PNG
(7-ethoxy-2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazo...)
Show SMILES CCOc1cccc2c(c(nn12)-c1ccc(F)cc1)-c1ccncc1
Show InChI InChI=1S/C20H16FN3O/c1-2-25-18-5-3-4-17-19(14-10-12-22-13-11-14)20(23-24(17)18)15-6-8-16(21)9-7-15/h3-13H,2H2,1H3
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

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Similars

Article
PubMed
n/an/a 50n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coli


Bioorg Med Chem Lett 18: 5428-30 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.040
BindingDB Entry DOI: 10.7270/Q27S7NM9
More data for this
Ligand-Target Pair