BDBM50275777 CHEMBL471009::N-(4-chlorophenethyl)-N-(1,4-dioxaspiro[4.5]decan-8-yl)isoquinoline-5-carboxamide

SMILES Clc1ccc(CCN(C2CCC3(CC2)OCCO3)C(=O)c2cccc3cnccc23)cc1

InChI Key InChIKey=RGJDKQYZMPZKCU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50275777   

TargetC5a anaphylatoxin chemotactic receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50275777(CHEMBL471009 | N-(4-chlorophenethyl)-N-(1,4-dioxas...)
Affinity DataIC50:  110nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed