BDBM50276348 (2R, aS)-3,4-dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)-phenyl]-a-(trifluoromethyl)-1(2H)-quinolineethanol::(2R,alphaS)-3,4-Dihydro-2-[3-(1,1,2,2-tetrafluoroethoxy)phenyl]-5-[3-(trifluoromethoxy)-phenyl]-alpha-(trifluoromethyl)-1(2H)-quinolineethanol::CHEMBL516439
SMILES O[C@@H](CN1[C@H](CCc2c1cccc2-c1cccc(OC(F)(F)F)c1)c1cccc(OC(F)(F)C(F)F)c1)C(F)(F)F
InChI Key InChIKey=GUUGXBLNGYDANT-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50276348
TargetCholesteryl ester transfer protein(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of human plasma-derived CETP activity by scintillation proximity assayMore data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 200nMAssay Description:Inhibition of CETP-mediated transfer of [3H]cholesteryl ester from HDL in human plasma after 18 hrsMore data for this Ligand-Target Pair
TargetCholesteryl ester transfer protein(Human)
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Johnson and Johnson Pharmaceutical Research and Development
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of CETP-mediated transfer of cholesteryl ester to LDL/VLDL in human plasma by Roar assayMore data for this Ligand-Target Pair