BDBM50276644 CHEMBL455221::trans-2-Aminomethyl-5-(5''-fluoro-2''-methoxyphenyl-4'-butyl)tetrahydrofuran

SMILES COc1ccc(F)cc1CCCC[C@H]1CC[C@H](CN)O1

InChI Key InChIKey=XPMTXFPUXPYNCB-LSDHHAIUSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50276644   

TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276644(CHEMBL455221 | trans-2-Aminomethyl-5-(5''-fluoro-2...)
Affinity DataKi:  4nMAssay Description:Displacement of [125I]RTI55 from human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276644(CHEMBL455221 | trans-2-Aminomethyl-5-(5''-fluoro-2...)
Affinity DataKi:  2.22E+3nMAssay Description:Displacement of [125I]RTI55 from human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276644(CHEMBL455221 | trans-2-Aminomethyl-5-(5''-fluoro-2...)
Affinity DataKi:  3.87E+3nMAssay Description:Displacement of [125I]RTI55 from human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276644(CHEMBL455221 | trans-2-Aminomethyl-5-(5''-fluoro-2...)
Affinity DataIC50:  1.65E+4nMAssay Description:Inhibition of [3H]dopamine reuptake at human DAT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276644(CHEMBL455221 | trans-2-Aminomethyl-5-(5''-fluoro-2...)
Affinity DataIC50:  84nMAssay Description:Inhibition of [3H]serotonin reuptake at human SERT expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM50276644(CHEMBL455221 | trans-2-Aminomethyl-5-(5''-fluoro-2...)
Affinity DataIC50:  7.12E+3nMAssay Description:Inhibition of [3H]norepinephrine reuptake at human NET expressed in HEK cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed