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BDBM50277257 6-(N-acetylsulfamoylamino)-N-(biphenyl-3-yl)hexanamide::CHEMBL515256

SMILES: CC(=O)NS(=O)(=O)NCCCCCC(=O)Nc1cccc(c1)-c1ccccc1

InChI Key: InChIKey=DIRLYZLGEIUOQK-UHFFFAOYSA-N

Data: 2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277257   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cereblon/Histone deacetylase 6


(Homo sapiens (Human))
BDBM50277257
PNG
(6-(N-acetylsulfamoylamino)-N-(biphenyl-3-yl)hexana...)
Show SMILES CC(=O)NS(=O)(=O)NCCCCCC(=O)Nc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C20H25N3O4S/c1-16(24)23-28(26,27)21-14-7-3-6-13-20(25)22-19-12-8-11-18(15-19)17-9-4-2-5-10-17/h2,4-5,8-12,15,21H,3,6-7,13-14H2,1H3,(H,22,25)(H,23,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



MethylGene Inc

Curated by ChEMBL


Assay Description
Inhibition of human recombinant N-terminal histidine-tagged HDAC6 expressed in baculovirus by fluorimetry


Bioorg Med Chem Lett 19: 336-40 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.081
BindingDB Entry DOI: 10.7270/Q2416WXB
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))
BDBM50277257
PNG
(6-(N-acetylsulfamoylamino)-N-(biphenyl-3-yl)hexana...)
Show SMILES CC(=O)NS(=O)(=O)NCCCCCC(=O)Nc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C20H25N3O4S/c1-16(24)23-28(26,27)21-14-7-3-6-13-20(25)22-19-12-8-11-18(15-19)17-9-4-2-5-10-17/h2,4-5,8-12,15,21H,3,6-7,13-14H2,1H3,(H,22,25)(H,23,24)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
antibodypedia
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



MethylGene Inc

Curated by ChEMBL


Assay Description
Inhibition of human recombinant C-terminal FLAG-tagged HDAC1 expressed in baculovirus by fluorimetry


Bioorg Med Chem Lett 19: 336-40 (2008)


Article DOI: 10.1016/j.bmcl.2008.11.081
BindingDB Entry DOI: 10.7270/Q2416WXB
More data for this
Ligand-Target Pair