BDBM50277476 4'-(2-{[(2R)-2-Hydroxy-2-phenylethyl]amino}ethyl)-3-isopropoxy-N-(methylsulfonyl)biphenyl-4-carboxamide Hydrochloride::CHEMBL515397

SMILES CC(C)Oc1cc(ccc1C(=O)NS(C)(=O)=O)-c1ccc(CCNC[C@H](O)c2ccccc2)cc1

InChI Key InChIKey=RJTZTNJDJLXFEL-VWLOTQADSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50277476   

TargetBeta-3 adrenergic receptor(Canis familiaris)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50277476(4'-(2-{[(2R)-2-Hydroxy-2-phenylethyl]amino}ethyl)-...)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at dog recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50277476(4'-(2-{[(2R)-2-Hydroxy-2-phenylethyl]amino}ethyl)-...)
Affinity DataEC50:  3.10nMAssay Description:Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Canis familiaris)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50277476(4'-(2-{[(2R)-2-Hydroxy-2-phenylethyl]amino}ethyl)-...)
Affinity DataEC50:  4.90nMAssay Description:Agonist activity at dog recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50277476(4'-(2-{[(2R)-2-Hydroxy-2-phenylethyl]amino}ethyl)-...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human recombinant beta-1 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50277476(4'-(2-{[(2R)-2-Hydroxy-2-phenylethyl]amino}ethyl)-...)
Affinity DataEC50:  3.10nMAssay Description:Agonist activity at human recombinant beta3 adrenergic receptor expressed in CHO cells assessed as cAMP accumulation by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed