BDBM50277548 CHEMBL4173394
SMILES [Na;v0+].[#6]-[#6]-[#8]-c1ccc(-[#7]-c2ccc(cc2)-[#6](=[#6]-2\[#6]=[#6]/[#6](/[#6]=[#6]-2-[#6])=[#7+](/[#6]-[#6])-[#6]-c2cccc(c2)S([#8-])(=O)=O)\c2ccc(cc2-[#6])-[#7](-[#6]-[#6])-[#6]-c2cccc(c2)S([#8-])(=O)=O)cc1
InChI Key InChIKey=YVNQAIFQFWTPLQ-UHFFFAOYSA-M
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50277548
Affinity DataIC50: 536nMAssay Description:Antagonist activity at human P2X7R expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake preincubated for 10 mins fo...More data for this Ligand-Target Pair
Affinity DataIC50: 1.52E+4nMAssay Description:Antagonist activity at P2X7R in Swiss Webster mouse peritoneal macrophages assessed as inhibition of ATP-induced propidium iodide uptake preincubated...More data for this Ligand-Target Pair
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of wild type alpha-synuclein (unknown origin) aggregation expressed in Escherichia coli BL21 after 30 days by thioflavin T staining-based ...More data for this Ligand-Target Pair
Affinity DataIC50: 343nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.37E+3nMAssay Description:Antagonist activity at human P2X7R expressed in HEK293 cells assessed as inhibition of ATP-induced ethidium iodide uptake preincubated for 5 mins fol...More data for this Ligand-Target Pair
Affinity DataIC50: 407nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced platelet aggregation in human whole bloodMore data for this Ligand-Target Pair
Affinity DataIC50: 109nMAssay Description:Antagonist activity at P2X7 receptor in Swiss mouse peritoneal macrophages assessed as inhibition of ATP-induced current at holding potential of -60 ...More data for this Ligand-Target Pair
Affinity DataIC50: 432nMAssay Description:Compound was evaluated to inactivate the bacterial AdoMet-DC; value ranges from 3.8 to 39.6 uMMore data for this Ligand-Target Pair
Affinity DataIC50: 552nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619 induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair