BDBM50277583 2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin-4-yl)phenyl]pyrimidin-2-amine, 5::4-Methyl-5-(2-(4-morpholinophenylamino)pyrimidin-4-yl)thiazol-2-amine::Aminopyrimidine, 9::CHEMBL482967::CYC-116

SMILES: Cc1nc(N)sc1-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1

InChI Key: InChIKey=GPSZYOIFQZPWEJ-UHFFFAOYSA-N

Data: 23 KI  12 IC50  1 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 36 hits for monomerid = 50277583   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G1/S-specific cyclin-E1 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase C (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
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G1/S-specific cyclin-D1 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-A2/Cyclin-dependent kinase 2 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
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Ferrochelatase, mitochondrial [R115L] (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		9.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-T1/Cyclin-dependent kinase 9 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 9 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase beta-1 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		820	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		2.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 7 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-H/Cyclin-dependent kinase 7 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 1 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 alpha (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM50277583 (2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin...) Show SMILES Show InChI	GoogleScholar	UniChem		>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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