BDBM50277676 2-(3-(8-hydroxy-5-methyl-6-oxo-5,6-dihydrophenanthridin-3-yl)propanamido)benzoic acid::CHEMBL485184

SMILES Cn1c2cc(CCC(=O)Nc3ccccc3C(O)=O)ccc2c2ccc(O)cc2c1=O

InChI Key InChIKey=OEIQJASFNKOLHW-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50277676   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277676(2-(3-(8-hydroxy-5-methyl-6-oxo-5,6-dihydrophenanth...)
Affinity DataIC50:  4.70E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277676(2-(3-(8-hydroxy-5-methyl-6-oxo-5,6-dihydrophenanth...)
Affinity DataEC50:  2.60E+3nMAssay Description:Agonist activity at human GPR109A expressed in CHOK1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHydroxycarboxylic acid receptor 2(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277676(2-(3-(8-hydroxy-5-methyl-6-oxo-5,6-dihydrophenanth...)
Affinity DataIC50:  340nMAssay Description:Displacement of [3H]niacin from human GPR109A expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed