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BDBM50277725 5-(4-Chlorophenyl)-N-(cycloheptanecarboxamidomethyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide::CHEMBL482957

SMILES: Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NCNC(=O)C1CCCCCC1

InChI Key: InChIKey=VTBQAIZAOGRGJU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277725   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50277725
PNG
(5-(4-Chlorophenyl)-N-(cycloheptanecarboxamidomethy...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NCNC(=O)C1CCCCCC1
Show InChI InChI=1S/C26H27Cl3N4O2/c1-16-23(26(35)31-15-30-25(34)18-6-4-2-3-5-7-18)32-33(22-13-12-20(28)14-21(22)29)24(16)17-8-10-19(27)11-9-17/h8-14,18H,2-7,15H2,1H3,(H,30,34)(H,31,35)
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Similars

Article
PubMed
n/an/a 75.6n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55940 from CB1R in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 17: 3080-92 (2009)


Article DOI: 10.1016/j.bmc.2009.03.006
BindingDB Entry DOI: 10.7270/Q22V2G0D
More data for this
Ligand-Target Pair