BDBM50277784 CHEMBL484928::N,N,2-trimethyl-5-nitrobenzenesulfonamide
SMILES CN(C)S(=O)(=O)c1cc(ccc1C)[N+]([O-])=O
InChI Key InChIKey=IFIUFCJFLGCQPH-UHFFFAOYSA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50277784
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant PDE4B2 assessed after 60 mins by IMAP fluorescence polarization assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of human recombinant PDE4D3 assessed after 60 mins by IMAP fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant PDE7A1 assessed as inhibition of hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant PDE7A1 expressed in baculovirus-infected insect Sf9 cells by modified two-step methodMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of human recombinant PDE7A1-mediated [3H]cAMP hydrolysis after 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Displacement of [3H]-cAMP from recombinant human PDE7A1 incubated for 20 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of human GST-tagged PDE4B expressed in baculovirus infected Sf9 insect cells using cAMP as substrate after 10 mins by PDE-Glo Phosphodiest...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 1.75E+5nMAssay Description:Inhibition of recombinant human PDE4B using cAMP as substrate after 10 mins by PDE-Glo Phosphodiesterase AssayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human PDE7A using cAMP as substrate after 10 mins by PDE-Glo Phosphodiesterase AssayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of human recombinant PDE7A using cAMP as substrate incubated for 20 mins measured by Kinase Glo reagent based microplate reader assayMore data for this Ligand-Target Pair
TargetHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A(Homo sapiens (Human))
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Centro De Investigaciones Biol�Gicas (Csic)
Curated by ChEMBL
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human GST-tagged PDE7A expressed in baculovirus infected Sf9 insect cells using cAMP as substrate after 10 mins by PDE-Glo Phosphodiest...More data for this Ligand-Target Pair