BDBM50277889 CARFILZOMIB::CHEMBL451887

SMILES: CC(C)C[C@H](NC(=O)[C@H](CCc1ccccc1)NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1

InChI Key: InChIKey=BLMPQMFVWMYDKT-UHFFFAOYSA-N

Data: 48 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 48 hits for monomerid = 50277889   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-8 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.81E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
A5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
A5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
A5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-9 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-10 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-6 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	890	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-7 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysosomal protective protein (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin G (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin B (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-7 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glutathione S-transferase omega-1 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
A5LHX3/O14818/P20618/P25786/P25787/P25788/P25789/P28062/P28065/P28066/P28070/P28072/P28074/P40306/P49720/P49721/P60900/Q8TAA3/Q99436 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	203	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
mRNA cap guanine-N7 methyltransferase (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
mRNA cap guanine-N7 methyltransferase (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	825	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-9 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-1 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-9 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proteasome subunit beta type-10 (Human)	BDBM50277889 (CHEMBL451887 | CARFILZOMIB) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair