BDBM50277910 4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyrazol-3-yl)cyclohexanol::CHEMBL507249

SMILES: O[C@H]1CC[C@@H](CC1)c1[nH]ncc1-c1ccnc(NC2CCCC2)n1

InChI Key: InChIKey=JCJAEEODSKNKTC-UHFFFAOYSA-N

Data: 1 KI  20 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50277910   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 14 (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C theta type (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase beta-1 (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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5'-AMP-activated protein kinase catalytic subunit alpha-2 (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 6 (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-activated protein kinase 2 (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 12 (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 13 (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 4 (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 7 (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10 (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 9 (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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MAP kinase-activated protein kinase 2 (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM50277910 (4-(4-(2-(cyclopentylamino)pyrimidin-4-yl)-1H-pyraz...) Show SMILES Show InChI	GoogleScholar	UniChem		12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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