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BDBM50277928 CHEMBL484774::{[(6-Amino-9-phenethyl-9H-purin-8-ylmethyl)-amino]-methyl}-phosphonic acid

SMILES: Nc1ncnc2n(CCc3ccccc3)c(CNCP(O)(O)=O)nc12

InChI Key: InChIKey=CNFYHKANVOBUSQ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277928   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fructose-1,6-bisphosphatase 1 (FBPase)


(Homo sapiens (Human))
BDBM50277928
PNG
(CHEMBL484774 | {[(6-Amino-9-phenethyl-9H-purin-8-y...)
Show SMILES Nc1ncnc2n(CCc3ccccc3)c(CNCP(O)(O)=O)nc12
Show InChI InChI=1S/C15H19N6O3P/c16-14-13-15(19-9-18-14)21(7-6-11-4-2-1-3-5-11)12(20-13)8-17-10-25(22,23)24/h1-5,9,17H,6-8,10H2,(H2,16,18,19)(H2,22,23,24)
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



Metabasis Therapeutics Inc

Curated by ChEMBL


Assay Description
Inhibition of human liver FBPase expressed in Escherichia coli by spectrophotometry


J Med Chem 52: 2880-98 (2009)


Article DOI: 10.1021/jm900078f
BindingDB Entry DOI: 10.7270/Q2V40V20
More data for this
Ligand-Target Pair