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BDBM50278005 (R)-5-methyl-3-(4-(pyridin-3-yl)benzyl)oxazolidin-2-one::CHEMBL525075

SMILES: C[C@@H]1CN(Cc2ccc(cc2)-c2cccnc2)C(=O)O1

InChI Key: InChIKey=MSFXHUHCIVALKI-GFCCVEGCSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278005   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 2


(Homo sapiens (Human))
BDBM50278005
PNG
((R)-5-methyl-3-(4-(pyridin-3-yl)benzyl)oxazolidin-...)
Show SMILES C[C@@H]1CN(Cc2ccc(cc2)-c2cccnc2)C(=O)O1
Show InChI InChI=1S/C16H16N2O2/c1-12-10-18(16(19)20-12)11-13-4-6-14(7-5-13)15-3-2-8-17-9-15/h2-9,12H,10-11H2,1H3/t12-/m1/s1
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Article
PubMed
n/an/an/an/a 7.55E+3n/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Agonist activity at mGluR2 (unknown origin) expressed in HEK cells by FLIPR assay in presence of glutamate


Bioorg Med Chem Lett 19: 2524-9 (2009)


Article DOI: 10.1016/j.bmcl.2009.03.032
BindingDB Entry DOI: 10.7270/Q2F18ZK7
More data for this
Ligand-Target Pair