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BDBM50278070 5-Hydroxy-2-methyl-4-thioxo-4H-pyran-3-carboxylic acid 4-methoxy-benzylamide::CHEMBL482961

SMILES: COc1ccc(CNC(=O)c2c(C)occ(O)c2=S)cc1

InChI Key: InChIKey=JDHGPTDYDICLJB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278070   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM50278070
PNG
(5-Hydroxy-2-methyl-4-thioxo-4H-pyran-3-carboxylic ...)
Show SMILES COc1ccc(CNC(=O)c2c(C)occ(O)c2=S)cc1
Show InChI InChI=1S/C15H15NO4S/c1-9-13(14(21)12(17)8-20-9)15(18)16-7-10-3-5-11(19-2)6-4-10/h3-6,8,17H,7H2,1-2H3,(H,16,18)
PDB
MMDB

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Similars

Article
PubMed
n/an/a 3.00E+4n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of human MMP2 catalytic domain by fluorescent substrate assay


Bioorg Med Chem Lett 19: 1970-6 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.044
BindingDB Entry DOI: 10.7270/Q2H99536
More data for this
Ligand-Target Pair