BDBM50278477 (R)-N-methyl-N-(pyrrolidin-3-yl)naphthalene-2-sulfonamide::CHEMBL469605

SMILES CN([C@@H]1CCNC1)S(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=ZCVDRKAWDMMKKP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50278477   

TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50278477((R)-N-methyl-N-(pyrrolidin-3-yl)naphthalene-2-sulf...)
Affinity DataIC50: 138nMAssay Description:Inhibition of radiolabeled serotonin reuptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50278477((R)-N-methyl-N-(pyrrolidin-3-yl)naphthalene-2-sulf...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of radiolabeled noradrenaline reuptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed