BDBM50278532 CHEMBL471034::N-(2-amino-1-phenylethyl)-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide

SMILES NCC(NC(=O)c1ccc(s1)-c1ccnc2[nH]ccc12)c1ccccc1

InChI Key InChIKey=TWYNGDRSMHRPSY-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50278532   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278532(CHEMBL471034 | N-(2-amino-1-phenylethyl)-5-(1H-pyr...)
Affinity DataIC50:  190nMAssay Description:Inhibition of AKT1 expressed in Escherichia coli or baculovirus-infected insect cells by scintillation proximity assayMore data for this Ligand-Target Pair
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50278532(CHEMBL471034 | N-(2-amino-1-phenylethyl)-5-(1H-pyr...)
Affinity DataIC50:  6nMAssay Description:Inhibition of AKT1More data for this Ligand-Target Pair