BDBM50278675 (+/-)-cis-6-((4-(2-(3-Fluorophenethylamino)-ethoxy)-pyrrolidin-3-yl)methyl)-4-methyl-pyridin-2-amine::6-{[(3S,4S)-4-(2-{[2-(3-fluorophenyl)ethyl]amino}ethoxy)pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine::CHEMBL1278038::CHEMBL469987

SMILES: Cc1cc(nc(c1)N)C[C@H]2CNC[C@H]2OCCNCCc3cccc(c3)F

InChI Key: InChIKey=NESZTSPBRDBHCW-UHFFFAOYSA-N

Data: 10 KI  2 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50278675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nitric oxide synthase, brain (Rat)	BDBM50278675 (CHEMBL469987 | (+/-)-cis-6-((4-(2-(3-Fluoropheneth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rat)	BDBM50278675 (CHEMBL469987 | (+/-)-cis-6-((4-(2-(3-Fluoropheneth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rat)	BDBM50278675 (CHEMBL469987 | (+/-)-cis-6-((4-(2-(3-Fluoropheneth...) Show SMILES Show InChI	GoogleScholar	UniChem		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rat)	BDBM50278675 (CHEMBL469987 | (+/-)-cis-6-((4-(2-(3-Fluoropheneth...) Show SMILES Show InChI	GoogleScholar	UniChem		15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mouse)	BDBM50278675 (CHEMBL469987 | (+/-)-cis-6-((4-(2-(3-Fluoropheneth...) Show SMILES Show InChI	GoogleScholar	UniChem		15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mouse)	BDBM50278675 (CHEMBL469987 | (+/-)-cis-6-((4-(2-(3-Fluoropheneth...) Show SMILES Show InChI	GoogleScholar	UniChem		9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rat)	BDBM50278675 (CHEMBL469987 | (+/-)-cis-6-((4-(2-(3-Fluoropheneth...) Show SMILES Show InChI	GoogleScholar	UniChem		9.50E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bovine)	BDBM50278675 (CHEMBL469987 | (+/-)-cis-6-((4-(2-(3-Fluoropheneth...) Show SMILES Show InChI	GoogleScholar	UniChem		3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bovine)	BDBM50278675 (CHEMBL469987 | (+/-)-cis-6-((4-(2-(3-Fluoropheneth...) Show SMILES Show InChI	GoogleScholar	UniChem		3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mouse)	BDBM50278675 (CHEMBL469987 | (+/-)-cis-6-((4-(2-(3-Fluoropheneth...) Show SMILES Show InChI	GoogleScholar	UniChem		1.16E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, endothelial (Bovine)	BDBM50278675 (CHEMBL469987 | (+/-)-cis-6-((4-(2-(3-Fluoropheneth...) Show SMILES Show InChI	GoogleScholar	UniChem		2.62E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rat)	BDBM50278675 (CHEMBL469987 | (+/-)-cis-6-((4-(2-(3-Fluoropheneth...) Show SMILES Show InChI	GoogleScholar	UniChem		7.50E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair