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BDBM50278775 (S)-2-(2,4,5-trifluorobenzyl)piperidine::CHEMBL469545

SMILES: Fc1cc(F)c(C[C@@H]2CCCCN2)cc1F

InChI Key: InChIKey=SZJYHGBXNMRYML-VIFPVBQESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50278775   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))
BDBM50278775
PNG
((S)-2-(2,4,5-trifluorobenzyl)piperidine | CHEMBL46...)
Show SMILES Fc1cc(F)c(C[C@@H]2CCCCN2)cc1F
Show InChI InChI=1S/C12H14F3N/c13-10-7-12(15)11(14)6-8(10)5-9-3-1-2-4-16-9/h6-7,9,16H,1-5H2/t9-/m0/s1
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a>3.00E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human DPP4


Bioorg Med Chem Lett 19: 2220-3 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.099
BindingDB Entry DOI: 10.7270/Q2RN37QF
More data for this
Ligand-Target Pair