BDBM50279044 (Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenylamino)-methylene]-2,3-dihydro-1H-indole-6-carboxylic Acid Amide::CHEMBL497949

SMILES: NC(=O)c1ccc2C(C(=Nc3ccc(CN4CCCCC4)cc3)c3ccccc3)C(=O)Nc2c1

InChI Key: InChIKey=QMPQJWQHTDPWNU-UHFFFAOYSA-N

Data: 9 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50279044   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Human)	BDBM50279044 ((Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
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TGF-beta receptor type-1 (Human)	BDBM50279044 ((Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	369	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 1 (Human)	BDBM50279044 ((Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM50279044 ((Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	763	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin-like growth factor 1 receptor (Human)	BDBM50279044 ((Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Insulin receptor (Human)	BDBM50279044 ((Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4 (Human)	BDBM50279044 ((Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM50279044 ((Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor tyrosine-protein kinase erbB-2 (Human)	BDBM50279044 ((Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM50279044 ((Z)-2-oxo-3-[Phenyl-(4-piperidin-1-ylmethyl-phenyl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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