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BDBM50279064 5-(4-nitrophenylsulfonyl)-5H-dibenzo[b,d]azepin-7(6H)-one::CHEMBL498087

SMILES: [O-][N+](=O)c1ccc(cc1)S(=O)(=O)N1CC(=O)c2ccccc2-c2ccccc12

InChI Key: InChIKey=UGYPGGXSHRXBAA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279064   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Voltage-gated potassium channel


(Homo sapiens (Human))
BDBM50279064
PNG
(5-(4-nitrophenylsulfonyl)-5H-dibenzo[b,d]azepin-7(...)
Show SMILES [O-][N+](=O)c1ccc(cc1)S(=O)(=O)N1CC(=O)c2ccccc2-c2ccccc12
Show InChI InChI=1S/C20H14N2O5S/c23-20-13-21(28(26,27)15-11-9-14(10-12-15)22(24)25)19-8-4-3-6-17(19)16-5-1-2-7-18(16)20/h1-12H,13H2
PDB
MMDB

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Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



4SC AG

Curated by ChEMBL


Assay Description
Inhibition of cloned Kv1.3 channel (unknown origin) expressed in mammalian cells by whole cell patch clamp assay


Bioorg Med Chem Lett 19: 2299-304 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.077
BindingDB Entry DOI: 10.7270/Q29K4B38
More data for this
Ligand-Target Pair