BindingDB logo
myBDB logout

BDBM50279249 (Z)-2-(Cyclohexylamino)-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-3,5-dihydro-4H-imidazol-4-one::CHEMBL499637

SMILES: O=C1NC(NC2CCCCC2)=NC1=Cc1c[nH]c2ncccc12

InChI Key: InChIKey=KOGUGDKKVKMGTR-ZROIWOOFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279249   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
CDC7/DBF4 (Cell division cycle 7-related protein kinase/Activator of S phase kinase)


(Homo sapiens (Human))
BDBM50279249
PNG
((Z)-2-(Cyclohexylamino)-5-(1H-pyrrolo[2,3-b]pyridi...)
Show SMILES O=C1NC(NC2CCCCC2)=NC1=Cc1c[nH]c2ncccc12
Show InChI InChI=1S/C17H19N5O/c23-16-14(9-11-10-19-15-13(11)7-4-8-18-15)21-17(22-16)20-12-5-2-1-3-6-12/h4,7-10,12H,1-3,5-6H2,(H,18,19)(H2,20,21,22,23)/b14-9-
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 21n/an/an/an/an/an/a



Nerviano Medical Sciences

Curated by ChEMBL


Assay Description
Inhibition of Cdc7 (unknown origin)-mediated phosphorylation of Mcm2


J Med Chem 52: 4380-90 (2009)


Article DOI: 10.1021/jm900248g
BindingDB Entry DOI: 10.7270/Q2FF3S8C
More data for this
Ligand-Target Pair