BDBM50279269 (Z)-3-({4-[(3-Dimethylaminopropyl)-methyl-carbamoyl]-phenylamino}-phenyl-methylene)-2-oxo-2,3-dihydro-1H-indole-6-carboxylicAcid Methyl Ester::CHEMBL525550

SMILES COC(=O)c1ccc2C(C(=Nc3ccc(cc3)C(=O)N(C)CCN(C)C)c3ccccc3)C(=O)Nc2c1

InChI Key InChIKey=ZMYSTIZWTSDYEP-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50279269   

TargetPlatelet-derived growth factor receptor alpha(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279269((Z)-3-({4-[(3-Dimethylaminopropyl)-methyl-carbamoy...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human PDGFRalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279269((Z)-3-({4-[(3-Dimethylaminopropyl)-methyl-carbamoy...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human VEGFR2 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 3(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279269((Z)-3-({4-[(3-Dimethylaminopropyl)-methyl-carbamoy...)
Affinity DataIC50: 59nMAssay Description:Inhibition of human VEGFR3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279269((Z)-3-({4-[(3-Dimethylaminopropyl)-methyl-carbamoy...)
Affinity DataIC50: 88nMAssay Description:Inhibition of human FGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
Boehringer Ingelheim Pharma

Curated by ChEMBL
LigandPNGBDBM50279269((Z)-3-({4-[(3-Dimethylaminopropyl)-methyl-carbamoy...)
Affinity DataIC50: 325nMAssay Description:Inhibition of human VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed