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BDBM50279881 3-[(E)-2-(3,4,5-Trimethoxy-phenyl)-vinyl]-pyridine; compound with 3-bromo-propionic acid methyl ester::CHEMBL300635::CHEMBL69896

SMILES: COc1cc(\C=C\c2cccnc2)cc(OC)c1OC

InChI Key: InChIKey=XTJNJMOYKKLUOV-VOTSOKGWSA-N

Data: 3 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50279881   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50279881
PNG
(3-[(E)-2-(3,4,5-Trimethoxy-phenyl)-vinyl]-pyridine...)
Show SMILES COc1cc(\C=C\c2cccnc2)cc(OC)c1OC
Show InChI InChI=1S/C16H17NO3/c1-18-14-9-13(10-15(19-2)16(14)20-3)7-6-12-5-4-8-17-11-12/h4-11H,1-3H3/b7-6+
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a>1.83E+6n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of angiotensin I phosphorylation catalyzed by the protein-tyrosine kinase p56 lck partially purified from bovine thymus.


Bioorg Med Chem Lett 1: 211-214 (1991)


Article DOI: 10.1016/S0960-894X(00)80254-1
BindingDB Entry DOI: 10.7270/Q2H70FP1
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50279881
PNG
(3-[(E)-2-(3,4,5-Trimethoxy-phenyl)-vinyl]-pyridine...)
Show SMILES COc1cc(\C=C\c2cccnc2)cc(OC)c1OC
Show InChI InChI=1S/C16H17NO3/c1-18-14-9-13(10-15(19-2)16(14)20-3)7-6-12-5-4-8-17-11-12/h4-11H,1-3H3/b7-6+
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 5.16E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of angiotensin I phosphorylation catalyzed by the protein-tyrosine kinase p56 lck partially purified from bovine thymus.


Bioorg Med Chem Lett 1: 211-214 (1991)


Article DOI: 10.1016/S0960-894X(00)80254-1
BindingDB Entry DOI: 10.7270/Q2H70FP1
More data for this
Ligand-Target Pair
Tyrosine-protein kinase Lck


(Homo sapiens (Human))
BDBM50279881
PNG
(3-[(E)-2-(3,4,5-Trimethoxy-phenyl)-vinyl]-pyridine...)
Show SMILES COc1cc(\C=C\c2cccnc2)cc(OC)c1OC
Show InChI InChI=1S/C16H17NO3/c1-18-14-9-13(10-15(19-2)16(14)20-3)7-6-12-5-4-8-17-11-12/h4-11H,1-3H3/b7-6+
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 5.16E+5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of p56 Lck tyrosine kinase


Bioorg Med Chem Lett 4: 1729-1732 (1994)


Article DOI: 10.1016/S0960-894X(00)80370-4
BindingDB Entry DOI: 10.7270/Q29C6XCK
More data for this
Ligand-Target Pair