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BDBM50279944 (R)-2-(2-Carboxymethyl-3-oxo-2,3,4,5-tetrahydro-1H-benzo[c]azepin-4-ylamino)-4-phenyl-butyric acid::CHEMBL107695

SMILES: OC(=O)CN1Cc2ccccc2CC(N[C@H](CCc2ccccc2)C(O)=O)C1=O

InChI Key: InChIKey=WISWGINCJUEDBR-MRTLOADZSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50279944   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin-converting enzyme


(Homo sapiens (human))
BDBM50279944
PNG
((R)-2-(2-Carboxymethyl-3-oxo-2,3,4,5-tetrahydro-1H...)
Show SMILES OC(=O)CN1Cc2ccccc2CC(N[C@H](CCc2ccccc2)C(O)=O)C1=O
Show InChI InChI=1S/C22H24N2O5/c25-20(26)14-24-13-17-9-5-4-8-16(17)12-19(21(24)27)23-18(22(28)29)11-10-15-6-2-1-3-7-15/h1-9,18-19,23H,10-14H2,(H,25,26)(H,28,29)/t18-,19?/m1/s1
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Similars

Article
10n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory constant of the compound was tested angiotensin converting enzyme


Bioorg Med Chem Lett 1: 309-312 (1991)


Article DOI: 10.1016/S0960-894X(01)80814-3
BindingDB Entry DOI: 10.7270/Q208657V
More data for this
Ligand-Target Pair