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BDBM50280563 1-Aza-bicyclo[2.2.1]heptan-3-one O-(4-methoxy-but-2-ynyl)-oxime::CHEMBL168991

SMILES: COCC#CCO\N=C1/CN2CCC1C2

InChI Key: InChIKey=ANTVCMHSNDCZOH-VAWYXSNFSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50280563   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Muscarinic acetylcholine receptor M2


(Homo sapiens (Human))
BDBM50280563
PNG
(1-Aza-bicyclo[2.2.1]heptan-3-one O-(4-methoxy-but-...)
Show SMILES COCC#CCO\N=C1/CN2CCC1C2
Show InChI InChI=1S/C11H16N2O2/c1-14-6-2-3-7-15-12-11-9-13-5-4-10(11)8-13/h10H,4-9H2,1H3/b12-11+
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 5.93E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against human Muscarinic acetylcholine receptor M2 using [3H]-quinuclidinyl benzilate to label antagonist site (RQNB) in CHO cell...


Bioorg Med Chem Lett 2: 821-826 (1992)


Article DOI: 10.1016/S0960-894X(00)80538-7
BindingDB Entry DOI: 10.7270/Q2PG1RNN
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor


(RAT)
BDBM50280563
PNG
(1-Aza-bicyclo[2.2.1]heptan-3-one O-(4-methoxy-but-...)
Show SMILES COCC#CCO\N=C1/CN2CCC1C2
Show InChI InChI=1S/C11H16N2O2/c1-14-6-2-3-7-15-12-11-9-13-5-4-10(11)8-13/h10H,4-9H2,1H3/b12-11+
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 55n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Compound was evaluated for inhibition of [3H]cis-methyldioxolane binding to label agonist sites (RCMD) in rat neocortex


Bioorg Med Chem Lett 2: 821-826 (1992)


Article DOI: 10.1016/S0960-894X(00)80538-7
BindingDB Entry DOI: 10.7270/Q2PG1RNN
More data for this
Ligand-Target Pair
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))
BDBM50280563
PNG
(1-Aza-bicyclo[2.2.1]heptan-3-one O-(4-methoxy-but-...)
Show SMILES COCC#CCO\N=C1/CN2CCC1C2
Show InChI InChI=1S/C11H16N2O2/c1-14-6-2-3-7-15-12-11-9-13-5-4-10(11)8-13/h10H,4-9H2,1H3/b12-11+
UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 4.24E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against human Muscarinic acetylcholine receptor M1 using [3H]-quinuclidinyl benzilate to label antagonist site (RQNB) in CHO cell...


Bioorg Med Chem Lett 2: 821-826 (1992)


Article DOI: 10.1016/S0960-894X(00)80538-7
BindingDB Entry DOI: 10.7270/Q2PG1RNN
More data for this
Ligand-Target Pair