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BDBM50280634 9-Amino-1,2,3,4-tetrahydro-acridine-1,7-diol::CHEMBL354601

SMILES: Nc1c2C(O)CCCc2nc2ccc(O)cc12

InChI Key: InChIKey=RIGISKTXVJDQAZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50280634   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acetylcholinesterase


(Rattus norvegicus (rat))
BDBM50280634
PNG
(9-Amino-1,2,3,4-tetrahydro-acridine-1,7-diol | CHE...)
Show SMILES Nc1c2C(O)CCCc2nc2ccc(O)cc12
Show InChI InChI=1S/C13H14N2O2/c14-13-8-6-7(16)4-5-9(8)15-10-2-1-3-11(17)12(10)13/h4-6,11,16-17H,1-3H2,(H2,14,15)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 1.06E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of acetylcholinesterase


Bioorg Med Chem Lett 2: 865-870 (1992)


Article DOI: 10.1016/S0960-894X(00)80546-6
BindingDB Entry DOI: 10.7270/Q25H7G51
More data for this
Ligand-Target Pair