BDBM50280646 2-[1-(1-Benzyl-piperidin-4-yl)-meth-(E)-ylidene]-5,6-dimethoxy-indan-1-one::CHEMBL168938

SMILES: COc1cc2c(cc1OC)C(=O)/C(=C/C3CCN(CC3)Cc4ccccc4)/C2

InChI Key: InChIKey=LPMOTUSFDTTWJL-UHFFFAOYSA-N

Data: 2 KI  6 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50280646   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Beta-secretase 1 (Human)	BDBM50280646 (2-[1-(1-Benzyl-piperidin-4-yl)-meth-(E)-ylidene]-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	697	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Mouse)	BDBM50280646 (2-[1-(1-Benzyl-piperidin-4-yl)-meth-(E)-ylidene]-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Mouse)	BDBM50280646 (2-[1-(1-Benzyl-piperidin-4-yl)-meth-(E)-ylidene]-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM50280646 (2-[1-(1-Benzyl-piperidin-4-yl)-meth-(E)-ylidene]-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
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Cholinesterase (Horse)	BDBM50280646 (2-[1-(1-Benzyl-piperidin-4-yl)-meth-(E)-ylidene]-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Electric eel)	BDBM50280646 (2-[1-(1-Benzyl-piperidin-4-yl)-meth-(E)-ylidene]-5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Human)	BDBM50280646 (2-[1-(1-Benzyl-piperidin-4-yl)-meth-(E)-ylidene]-5...) Show SMILES Show InChI	GoogleScholar	UniChem		35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cholinesterase (Horse)	BDBM50280646 (2-[1-(1-Benzyl-piperidin-4-yl)-meth-(E)-ylidene]-5...) Show SMILES Show InChI	GoogleScholar	UniChem		2.44E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair