BDBM50281274 CHEMBL4166822
SMILES COc1cc2c(NC3CCN(C)CC3)cc(nc2cc1OCCCN1CCCC1)C(F)(F)F
InChI Key InChIKey=UXDIXDDGEATWIR-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50281274
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Universidad De Oviedo-Principado De Asturias
Curated by ChEMBL
Universidad De Oviedo-Principado De Asturias
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Universidad De Oviedo-Principado De Asturias
Curated by ChEMBL
Universidad De Oviedo-Principado De Asturias
Curated by ChEMBL
Affinity DataIC50: 637nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair