BDBM50281274 CHEMBL4166822

SMILES COc1cc2c(NC3CCN(C)CC3)cc(nc2cc1OCCCN1CCCC1)C(F)(F)F

InChI Key InChIKey=UXDIXDDGEATWIR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50281274   

TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Universidad De Oviedo-Principado De Asturias

Curated by ChEMBL
LigandPNGBDBM50281274(CHEMBL4166822)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human DNMT1 using polydeoxyinosine polydeoxycytosine DNA as substrate after 15 mins in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone-lysine N-methyltransferase EHMT2(Homo sapiens (Human))
Universidad De Oviedo-Principado De Asturias

Curated by ChEMBL
LigandPNGBDBM50281274(CHEMBL4166822)
Affinity DataIC50:  637nMAssay Description:Inhibition of human G9a using biotinylated-H3K9 peptide as substrate after 1 hr in presence of SAM by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed