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BDBM50281485 1-(4-Butyl-phenyl)-3-(2,6-diisopropyl-phenyl)-urea::CHEMBL89544

SMILES: CCCCc1ccc(NC(=O)Nc2c(cccc2C(C)C)C(C)C)cc1

InChI Key: InChIKey=JIFJTLCMALFFTL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50281485   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acyl-CoA:cholesterol acyltransferase


(Oryctolagus cuniculus)
BDBM50281485
PNG
(1-(4-Butyl-phenyl)-3-(2,6-diisopropyl-phenyl)-urea...)
Show SMILES CCCCc1ccc(NC(=O)Nc2c(cccc2C(C)C)C(C)C)cc1
Show InChI InChI=1S/C23H32N2O/c1-6-7-9-18-12-14-19(15-13-18)24-23(26)25-22-20(16(2)3)10-8-11-21(22)17(4)5/h8,10-17H,6-7,9H2,1-5H3,(H2,24,25,26)
PDB

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PC sid
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Similars

Article
n/an/a 29n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibition of intestinal Acyl coenzyme A:cholesterol acyltransferase in cholesterol-fed rabbits.


Bioorg Med Chem Lett 3: 259-262 (1993)


Article DOI: 10.1016/S0960-894X(01)80888-X
BindingDB Entry DOI: 10.7270/Q2N58M9R
More data for this
Ligand-Target Pair