BDBM50281729 (4R,5S)-3-Oxo-4,5-diphenyl-pyrazolidine-1-carbothioic acid (4-chloro-3-trifluoromethyl-phenyl)-amide::CHEMBL354633::LY-294920

SMILES FC(F)(F)c1cc(NC(=S)N2NC(=O)[C@@H]([C@H]2c2ccccc2)c2ccccc2)ccc1Cl

InChI Key InChIKey=DFOIEDQSOJASSS-WOJBJXKFSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50281729   

TargetCholecystokinin receptor type A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50281729((4R,5S)-3-Oxo-4,5-diphenyl-pyrazolidine-1-carbothi...)
Affinity DataIC50:  42nMAssay Description:The compound was tested for its activity to inhibit the binding of [3H]-L-364,718 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCholecystokinin receptor type A(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50281729((4R,5S)-3-Oxo-4,5-diphenyl-pyrazolidine-1-carbothi...)
Affinity DataIC50:  17nMAssay Description:The compound was tested for its activity to inhibit the binding of [3H]-L-364,718 to Cholecystokinin type A receptor in rat pancreasMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281729((4R,5S)-3-Oxo-4,5-diphenyl-pyrazolidine-1-carbothi...)
Affinity DataIC50:  1.90E+3nMpH: 7.4Assay Description:The compound was tested for its activity to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in mouse brain at a pH of 6.5More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50281729((4R,5S)-3-Oxo-4,5-diphenyl-pyrazolidine-1-carbothi...)
Affinity DataIC50:  880nMpH: 7.4Assay Description:The compound was tested for its activity to inhibit the binding of [125I]-CCK-8 to Cholecystokinin type B receptor in mouse brain at a pH of 7.4More data for this Ligand-Target Pair
In DepthDetails Article