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BDBM50281781 Ac-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH::CHEMBL264534

SMILES: CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H](CC(C)C)C(O)=O

InChI Key: InChIKey=OYCOXIWUNFSKDJ-MNBFHEIESA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50281781   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neurotensin receptor 1


(MOUSE)
BDBM50281781
PNG
(Ac-Lys-Pro-Arg-Arg-Pro-Tyr-Ile-Leu-OH | CHEMBL2645...)
Show SMILES CC[C@@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(C)=O)C(=O)N[C@@H](CC(C)C)C(O)=O
Show InChI InChI=1S/C51H85N15O11/c1-6-30(4)41(46(73)63-38(49(76)77)27-29(2)3)64-43(70)37(28-32-18-20-33(68)21-19-32)62-45(72)40-17-12-26-66(40)48(75)36(15-10-24-58-51(55)56)61-42(69)34(14-9-23-57-50(53)54)60-44(71)39-16-11-25-65(39)47(74)35(59-31(5)67)13-7-8-22-52/h18-21,29-30,34-41,68H,6-17,22-28,52H2,1-5H3,(H,59,67)(H,60,71)(H,61,69)(H,62,72)(H,63,73)(H,64,70)(H,76,77)(H4,53,54,57)(H4,55,56,58)/t30-,34+,35+,36+,37+,38+,39+,40+,41+/m1/s1
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Similars

Article
0.0240n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of specific binding of [125I]-Tyr3-NT(1-13) to NT receptors in neonatal mouse whole brain (minus cerebellum)


Bioorg Med Chem Lett 3: 949-952 (1993)


Article DOI: 10.1016/S0960-894X(00)80698-8
BindingDB Entry DOI: 10.7270/Q2CJ8DDX
More data for this
Ligand-Target Pair