BDBM50282171 CHEMBL4176742

SMILES Cc1cc(N2CCN(CC2)c2nc(Cl)nc(Nc3cccc(c3)C(F)(F)F)n2)n2ncnc2n1

InChI Key InChIKey=GSLAMSZEEYMKPM-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50282171   

TargetAcetylcholinesterase(Electric eel)
Jamia Millia Islamia (Central University)

Curated by ChEMBL
LigandPNGBDBM50282171(CHEMBL4176742)
Affinity DataIC50: 65nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured after 2 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Jamia Millia Islamia (Central University)

Curated by ChEMBL
LigandPNGBDBM50282171(CHEMBL4176742)
Affinity DataKi:  69nMAssay Description:Mixed-type inhibition of electric eel AChE using varying levels of acetylthiocholine iodide as substrate preincubated for 15 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Jamia Millia Islamia (Central University)

Curated by ChEMBL
LigandPNGBDBM50282171(CHEMBL4176742)
Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Jamia Millia Islamia (Central University)

Curated by ChEMBL
LigandPNGBDBM50282171(CHEMBL4176742)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of HFIP-pretreated amyloid beta (1 to 42 residues) (unknown origin) self aggregation after 24 hrs by ThT-based fluorometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMed