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BDBM50282491 CHEMBL4168302

SMILES: CC(=O)Nc1ccc(O)c2ccccc12

InChI Key: InChIKey=KBJFWKRDRSFIBS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282491   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone acetyltransferase KAT8


(Homo sapiens (Human))
BDBM50282491
PNG
(CHEMBL4168302)
Show SMILES CC(=O)Nc1ccc(O)c2ccccc12
Show InChI InChI=1S/C12H11NO2/c1-8(14)13-11-6-7-12(15)10-5-3-2-4-9(10)11/h2-7,15H,1H3,(H,13,14)
PDB
MMDB

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PC sid
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Similars

Article
PubMed
n/an/a>5.00E+5n/an/an/an/an/an/a



University of Groningen

Curated by ChEMBL


Assay Description
Tested for antagonist activity against NK1 receptor in rabbit vena cava by using substance P (SP) as agonist


Eur J Med Chem 136: 480-486 (2017)


Article DOI: 10.1016/j.ejmech.2017.05.015
BindingDB Entry DOI: 10.7270/Q20Z75S9
More data for this
Ligand-Target Pair