BindingDB logo
myBDB logout

BDBM50282503 3,4-Dimethyl-7-(5-methyl-[1,3,4]oxadiazol-2-ylmethoxy)-chromen-2-one::CHEMBL18832

SMILES: Cc1nnc(COc2ccc3c(C)c(C)c(=O)oc3c2)o1

InChI Key: InChIKey=HAZCKGIPEIZFCN-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50282503   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM50282503
PNG
(3,4-Dimethyl-7-(5-methyl-[1,3,4]oxadiazol-2-ylmeth...)
Show SMILES Cc1nnc(COc2ccc3c(C)c(C)c(=O)oc3c2)o1
Show InChI InChI=1S/C15H14N2O4/c1-8-9(2)15(18)21-13-6-11(4-5-12(8)13)19-7-14-17-16-10(3)20-14/h4-6H,7H2,1-3H3
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 5.60E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory against monoamine oxidase A (MAO-A) in rat brain homogenate.


Bioorg Med Chem Lett 4: 1195-1198 (1994)


Article DOI: 10.1016/S0960-894X(01)80328-0
BindingDB Entry DOI: 10.7270/Q2QJ7HST
More data for this
Ligand-Target Pair
Monoamine Oxidase Type B (MAO-B)


(Rattus norvegicus (rat))
BDBM50282503
PNG
(3,4-Dimethyl-7-(5-methyl-[1,3,4]oxadiazol-2-ylmeth...)
Show SMILES Cc1nnc(COc2ccc3c(C)c(C)c(=O)oc3c2)o1
Show InChI InChI=1S/C15H14N2O4/c1-8-9(2)15(18)21-13-6-11(4-5-12(8)13)19-7-14-17-16-10(3)20-14/h4-6H,7H2,1-3H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
n/an/a 15n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro inhibitory activity against monoamine oxidase B (MAO-B) in rat brain homogenate.


Bioorg Med Chem Lett 4: 1195-1198 (1994)


Article DOI: 10.1016/S0960-894X(01)80328-0
BindingDB Entry DOI: 10.7270/Q2QJ7HST
More data for this
Ligand-Target Pair