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BDBM50282879 2-Butyl-6-((R)-2-methyl-hexahydro-cyclopenta[d]isoxazol-3-yl)-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-3H-quinazolin-4-one::CHEMBL53803

SMILES: CCCCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)[C@H]1C2CCCC2ON1C

InChI Key: InChIKey=HFSBXIQXFLGAIT-RKQLGKQKSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282879   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50282879
PNG
(2-Butyl-6-((R)-2-methyl-hexahydro-cyclopenta[d]iso...)
Show SMILES CCCCc1nc2ccc(cc2c(=O)n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)[C@H]1C2CCCC2ON1C
Show InChI InChI=1S/C33H35N7O2/c1-3-4-12-30-34-28-18-17-23(31-26-10-7-11-29(26)42-39(31)2)19-27(28)33(41)40(30)20-21-13-15-22(16-14-21)24-8-5-6-9-25(24)32-35-37-38-36-32/h5-6,8-9,13-19,26,29,31H,3-4,7,10-12,20H2,1-2H3,(H,35,36,37,38)/t26?,29?,31-/m0/s1
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Similars

Article
n/an/a 154n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity to angiotensin II receptor in bovine adrenal cortex


Bioorg Med Chem Lett 4: 1819-1824 (1994)


Article DOI: 10.1016/S0960-894X(01)80377-2
BindingDB Entry DOI: 10.7270/Q21V5DXH
More data for this
Ligand-Target Pair