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BDBM50282929 1-(3,5-Dichloro-benzyloxymethyl)-2,2-diphenyl-ethylamine::CHEMBL59380

SMILES: NC(COCc1cc(Cl)cc(Cl)c1)C(c1ccccc1)c1ccccc1

InChI Key: InChIKey=MDFSJQWVOCQTLX-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50282929   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neurokinin 1 receptor


(Homo sapiens (Human))
BDBM50282929
PNG
(1-(3,5-Dichloro-benzyloxymethyl)-2,2-diphenyl-ethy...)
Show SMILES NC(COCc1cc(Cl)cc(Cl)c1)C(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C22H21Cl2NO/c23-19-11-16(12-20(24)13-19)14-26-15-21(25)22(17-7-3-1-4-8-17)18-9-5-2-6-10-18/h1-13,21-22H,14-15,25H2
PDB
MMDB

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Similars

Article
n/an/a 11.3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity of the compound towards human Tachykinin receptor 1 expressed in CHO cells by the displacement of [125 I] substance P


Bioorg Med Chem Lett 4: 1903-1908 (1994)


Article DOI: 10.1016/S0960-894X(01)80531-X
BindingDB Entry DOI: 10.7270/Q2NK3DZ1
More data for this
Ligand-Target Pair