BDBM50282993 (2S,4R)-4-Cyclohexyl-2-hydroxy-3-((R)-3-methylsulfanyl-2-{2-[(morpholine-4-carbonyl)-amino]-3-phenyl-propionylamino}-propionylamino)-butyric acid isopropyl ester::CHEMBL60550

SMILES CSC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)N1CCOCC1)C(=O)N[C@@H](CC1CCCCC1)[C@@H](O)C(=O)OC(C)C

InChI Key InChIKey=UZQBKCWYZBHBOW-YIPNQBBMSA-N

Data  5 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50282993   

TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282993((2S,4R)-4-Cyclohexyl-2-hydroxy-3-((R)-3-methylsulf...)
Affinity DataIC50:  0.5nMAssay Description:Compound was tested for the inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282993((2S,4R)-4-Cyclohexyl-2-hydroxy-3-((R)-3-methylsulf...)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282993((2S,4R)-4-Cyclohexyl-2-hydroxy-3-((R)-3-methylsulf...)
Affinity DataIC50:  0.300nMAssay Description:Compound was tested for the inhibition of monkey plasma reninMore data for this Ligand-Target Pair
In DepthDetails Article
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50282993((2S,4R)-4-Cyclohexyl-2-hydroxy-3-((R)-3-methylsulf...)
Affinity DataIC50:  0.5nMAssay Description:Compound was tested for the inhibition of guinea pig plasma reninMore data for this Ligand-Target Pair
In DepthDetails Article
TargetCathepsin D(Bovine)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50282993((2S,4R)-4-Cyclohexyl-2-hydroxy-3-((R)-3-methylsulf...)
Affinity DataIC50:  24nMAssay Description:Inhibitory concentration on Bovine Cathepsin DMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed