BDBM50283303 2-methyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarbonylaminosulphonyl)-biphenyl-4-ylmethyl)-6-(N,N-dimethylaminocarbonylamino)-3H-quinazolin-4-one::CHEMBL305956

SMILES CN(C)C(=O)Nc1ccc2nc(C)n(Cc3ccc(cc3F)-c3ccccc3S(=O)(=O)NC(=O)OCCC3CC3)c(=O)c2c1

InChI Key InChIKey=YUGKBHWDRZZXSH-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50283303   

TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283303(2-methyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarb...)
Affinity DataIC50:  6.60nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II, type 2 of rat midbrain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283303(2-methyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarb...)
Affinity DataIC50:  12nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of human adrenal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283303(2-methyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarb...)
Affinity DataIC50:  2.40nMAssay Description:In vivo inhibitory concentration of the compound against AT2 receptor of rat adrenal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283303(2-methyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarb...)
Affinity DataIC50:  2.30nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of rabbit aorta membraneMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50283303(2-methyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarb...)
Affinity DataIC50:  2.30nMAssay Description:In vivo inhibitory concentration of the compound against AT2 receptor of rat adrenal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283303(2-methyl-3-(3-fluoro-2'-(2-cyclopropylethyloxycarb...)
Affinity DataIC50:  12nMAssay Description:In vivo inhibitory concentration of the compound against AT2 receptor of human adrenal membraneMore data for this Ligand-Target Pair
In DepthDetails Article