BDBM50283318 2-Butyl-3-(3-fluoro-2'-(butyloxycarbonylaminosulphonyl)-biphenyl-4-ylmethyl)-6-(isopropyl-methyl-aminocarbonylamino)-3H-quinazolin-4-one::CHEMBL415073

SMILES CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nc3ccc(NC(=O)N(C)C(C)C)cc3c2=O)c(F)c1

InChI Key InChIKey=YZRHNUCZSNUXFT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50283318   

TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283318(2-Butyl-3-(3-fluoro-2'-(butyloxycarbonylaminosulph...)
Affinity DataIC50:  0.770nMAssay Description:In vivo inhibitory concentration of the compound against AT2 receptor of rat adrenal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283318(2-Butyl-3-(3-fluoro-2'-(butyloxycarbonylaminosulph...)
Affinity DataIC50:  0.890nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of human adrenal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283318(2-Butyl-3-(3-fluoro-2'-(butyloxycarbonylaminosulph...)
Affinity DataIC50:  0.440nMAssay Description:In vivo inhibitory concentration against Angiotensin II, type 2 of rat midbrain membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-2 angiotensin II receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50283318(2-Butyl-3-(3-fluoro-2'-(butyloxycarbonylaminosulph...)
Affinity DataIC50:  7.70nMAssay Description:In vivo inhibitory concentration of the compound against AT2 receptor of human adrenal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50283318(2-Butyl-3-(3-fluoro-2'-(butyloxycarbonylaminosulph...)
Affinity DataIC50:  0.25nMAssay Description:In vivo inhibitory concentration against Angiotensin II receptor, type 1 of rat adrenal membraneMore data for this Ligand-Target Pair
In DepthDetails Article
TargetType-1 angiotensin II receptor(RABBIT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283318(2-Butyl-3-(3-fluoro-2'-(butyloxycarbonylaminosulph...)
Affinity DataIC50:  0.190nMAssay Description:In vivo inhibitory concentration of the compound against Angiotensin II receptor, type 1 of rabbit aorta membraneMore data for this Ligand-Target Pair
In DepthDetails Article