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BDBM50283401 (1-Benzyl-piperidin-4-yl)-phenyl-((E)-3-phenyl-allyl)-amine; compound with (E)-but-2-enedioic acid::CHEMBL115506

SMILES: C(\C=C\c1ccccc1)N(C1CCN(Cc2ccccc2)CC1)c1ccccc1

InChI Key: InChIKey=WXDFSBOGRSXWPP-XNTDXEJSSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50283401   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sigma non-opioid intracellular receptor 1


(Homo sapiens (Human))
BDBM50283401
PNG
((1-Benzyl-piperidin-4-yl)-phenyl-((E)-3-phenyl-all...)
Show SMILES C(\C=C\c1ccccc1)N(C1CCN(Cc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C27H30N2/c1-4-11-24(12-5-1)15-10-20-29(26-16-8-3-9-17-26)27-18-21-28(22-19-27)23-25-13-6-2-7-14-25/h1-17,27H,18-23H2/b15-10+
PDB

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
1.50E+3n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibiton of [3H]-(+)-SKF-10,047 binding to sigma receptor


Bioorg Med Chem Lett 4: 329-334 (1994)


Article DOI: 10.1016/S0960-894X(01)80138-4
BindingDB Entry DOI: 10.7270/Q20R9PBC
More data for this
Ligand-Target Pair
Serotonin 2 (5-HT2) receptor


(Homo sapiens (Human))
BDBM50283401
PNG
((1-Benzyl-piperidin-4-yl)-phenyl-((E)-3-phenyl-all...)
Show SMILES C(\C=C\c1ccccc1)N(C1CCN(Cc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C27H30N2/c1-4-11-24(12-5-1)15-10-20-29(26-16-8-3-9-17-26)27-18-21-28(22-19-27)23-25-13-6-2-7-14-25/h1-17,27H,18-23H2/b15-10+
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
>1.00E+4n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor


Bioorg Med Chem Lett 4: 329-334 (1994)


Article DOI: 10.1016/S0960-894X(01)80138-4
BindingDB Entry DOI: 10.7270/Q20R9PBC
More data for this
Ligand-Target Pair
D(2) dopamine receptor


(Homo sapiens (Human))
BDBM50283401
PNG
((1-Benzyl-piperidin-4-yl)-phenyl-((E)-3-phenyl-all...)
Show SMILES C(\C=C\c1ccccc1)N(C1CCN(Cc2ccccc2)CC1)c1ccccc1
Show InChI InChI=1S/C27H30N2/c1-4-11-24(12-5-1)15-10-20-29(26-16-8-3-9-17-26)27-18-21-28(22-19-27)23-25-13-6-2-7-14-25/h1-17,27H,18-23H2/b15-10+
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a>1.00E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Displacement of [3H]-spiperone from dopamine D2 receptor


Bioorg Med Chem Lett 4: 329-334 (1994)


Article DOI: 10.1016/S0960-894X(01)80138-4
BindingDB Entry DOI: 10.7270/Q20R9PBC
More data for this
Ligand-Target Pair