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BDBM50285344 CHEMBL40585::[4-(7-Methyl-2-propyl-imidazo[4,5-b]pyridin-3-ylmethyl)-phenoxy]-o-tolyl-acetic acid

SMILES: CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(C(O)=O)c2ccccc2C)cc1

InChI Key: InChIKey=XXHLCVDUVSKHAU-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50285344   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II type 1a (AT-1a) receptor


(RABBIT)
BDBM50285344
PNG
(CHEMBL40585 | [4-(7-Methyl-2-propyl-imidazo[4,5-b]...)
Show SMILES CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(C(O)=O)c2ccccc2C)cc1
Show InChI InChI=1/C26H27N3O3/c1-4-7-22-28-23-18(3)14-15-27-25(23)29(22)16-19-10-12-20(13-11-19)32-24(26(30)31)21-9-6-5-8-17(21)2/h5-6,8-15,24H,4,7,16H2,1-3H3,(H,30,31)
PDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 5n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Tested in vitro for Angiotensin II receptor, type 1 binding affinity using rabbit aorta binding assay


Bioorg Med Chem Lett 5: 155-158 (1995)


Article DOI: 10.1016/0960-894X(94)00476-V
BindingDB Entry DOI: 10.7270/Q26H4HC9
More data for this
Ligand-Target Pair