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BDBM50285468 {[(2S,3R,5R)-3-Azido-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethoxy]-hydroxy-phosphorylmethyl}-phosphonomethyl-phosphinic acid anion

SMILES: Cc1cn(C2CC(N=[N+]=[N-])C(COP([O-])(=O)CP([O-])(=O)CP([O-])([O-])=O)O2)c(=O)[nH]c1=O

InChI Key: InChIKey=DGAUZSHUMUJTDF-UHFFFAOYSA-J

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50285468   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human immunodeficiency virus type 1 reverse transcriptase


(Human immunodeficiency virus 1)
BDBM50285468
PNG
({[(2S,3R,5R)-3-Azido-5-(5-methyl-2,4-dioxo-3,4-dih...)
Show SMILES Cc1cn(C2CC(N=[N+]=[N-])C(COP([O-])(=O)CP([O-])(=O)CP([O-])([O-])=O)O2)c(=O)[nH]c1=O
Show InChI InChI=1S/C12H20N5O11P3/c1-7-3-17(12(19)14-11(7)18)10-2-8(15-16-13)9(28-10)4-27-31(25,26)6-29(20,21)5-30(22,23)24/h3,8-10H,2,4-6H2,1H3,(H,20,21)(H,25,26)(H,14,18,19)(H2,22,23,24)/p-4
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

Article
n/an/a 4.80E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibitory activity against HIV-1 reverse transcriptase


Bioorg Med Chem Lett 5: 2315-2320 (1995)


Article DOI: 10.1016/0960-894X(95)00401-E
BindingDB Entry DOI: 10.7270/Q2PG1S7P
More data for this
Ligand-Target Pair