BindingDB logo
myBDB logout

BDBM50285753 5-alpha-hydroxyacid imidazolyl biphenyl sulfonyl urea analogue::CHEMBL330302

SMILES: CCCCc1nc(SC)c(C(C)C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1

InChI Key: InChIKey=YVMCKTRCEGFQBI-UHFFFAOYNA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50285753   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II receptor (AT-1) type-1


(RAT)
BDBM50285753
PNG
(5-alpha-hydroxyacid imidazolyl biphenyl sulfonyl u...)
Show SMILES CCCCc1nc(SC)c(C(C)C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1
Show InChI InChI=1/C32H36N4O5S2/c1-4-5-15-28-34-30(42-3)29(22(2)31(37)38)36(28)21-24-16-18-25(19-17-24)26-13-9-10-14-27(26)43(40,41)35-32(39)33-20-23-11-7-6-8-12-23/h6-14,16-19,22H,4-5,15,20-21H2,1-3H3,(H,37,38)(H2,33,35,39)
PDB
MMDB

KEGG

UniProtKB/SwissProt

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 1.30n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity at Angiotensin II Type 1 receptor in rat liver membrane by [125I]AII displacement.


Bioorg Med Chem Lett 5: 2611-2616 (1995)


Article DOI: 10.1016/0960-894X(95)00479-D
BindingDB Entry DOI: 10.7270/Q2GT5N57
More data for this
Ligand-Target Pair
Angiotensin II receptor


(Homo sapiens (Human))
BDBM50285753
PNG
(5-alpha-hydroxyacid imidazolyl biphenyl sulfonyl u...)
Show SMILES CCCCc1nc(SC)c(C(C)C(O)=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)NCc1ccccc1
Show InChI InChI=1/C32H36N4O5S2/c1-4-5-15-28-34-30(42-3)29(22(2)31(37)38)36(28)21-24-16-18-25(19-17-24)26-13-9-10-14-27(26)43(40,41)35-32(39)33-20-23-11-7-6-8-12-23/h6-14,16-19,22H,4-5,15,20-21H2,1-3H3,(H,37,38)(H2,33,35,39)
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
n/an/a 3.80E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
In vitro binding affinity at Angiotensin II Type 2 receptor in rabbit uterus membrane by [125I]-AII displacement.


Bioorg Med Chem Lett 5: 2611-2616 (1995)


Article DOI: 10.1016/0960-894X(95)00479-D
BindingDB Entry DOI: 10.7270/Q2GT5N57
More data for this
Ligand-Target Pair